What is Multimodal Imaging? Multimodal Imaging is the combination of two or more imaging modalities that leverage the strengths of each modality. Multimodal imaging enhances the anatomical, functional, and molecular information obtained in a single imaging session. PhotoSound’s Tritom imaging system utilizes the same short pulse duration OPO light source to generate the photoacoustic as […]
Tag: in vivo
Tissue Engineering & Regeneration
What is Tissue Engineering & Regeneration? Tissue engineering is the process of creating new tissues and organs to replace damaged or diseased tissues. Photoacoustic tomography can be used to evaluate tissue regeneration and vascularization. PhotoSound Product Used TriTom Photoacoustic Image-Guided Delivery of Plasmonic-Nanoparticle-Labeled Mesenchymal Stem Cells to the Spinal Cord MoleculUS A Combined Ultrasound and […]
Disease Monitoring
PhotoSounds OEM Line of products is an ideal starting point for the development of custom systems where the parallel acquisition of multiple channels is required. All our ADCs are streaming and allow the continuous acquisition of data straight to the receiving computer for processing or storage. PhotoSound’s ADCs are feature-rich, they have multiple electronic and […]
Neuroimaging
What is Neuroimaging? Neuroimaging is the use of medical imaging techniques to study the structure and function of the nervous system, focusing on the brain. Photoacoustic tomography has been used to image the brain, spinal cord, and other parts of the nervous system. PhotoSound Product Used TriTom Monitoring Neonatal Brain Hemorrhage Progression by Photoacoustic Tomography […]
Anatomical Imaging
What is anatomical imaging? Anatomical imaging is used to visualize the structure and organization of tissues and organs within the body. Photoacoustic tomography generates high-resolution images of blood-rich tissues without the need for exogenous contrast agents. PhotoSound Product Used TriTom Dual-Scan Photoacoustic Tomography for the Imaging of Vascular Structure on Foot Photoacoustic tomography to assess […]
Therapeutic Monitoring
PhotoSounds OEM Line of products is an ideal starting point for the development of custom systems where the parallel acquisition of multiple channels is required. All our ADCs are streaming and allow the continuous acquisition of data straight to the receiving computer for processing or storage. PhotoSound’s ADCs are feature-rich, they have multiple electronic and […]
CO-REGISTERED PHOTOACOUSTIC AND FLUORESCENT IMAGING OF A SWITCHABLE NANOPROBE BASED ON J-AGGREGATES OF INDOCYANINE GREEN
Authors: Diego S. Dumani, Hans-Peter Brecht, Vassili Ivanov, Ryan Deschner, Justin T. Harris, Kimberly A. Homan, Jason R. Cook, Stanislav Y. Emelianov, Sergey A. Ermilov ABSTRACT We introduce a preclinical imaging platform – a 3D photoacoustic/fluorescence tomography (PAFT) instrument augmented with an environmentally responsive dual-contrast biocompatible nanoprobe. The PAFT instrument was designed for simultaneous acquisition […]
COMMERCIAL SMALL ANIMAL IMAGING COULD AID DISEASE DETECTION
Authors: Mark Little ABSTRACT The development of anticancer metastatic therapies for human clinical trials requires meticulous evaluation of efficacy and optimization of small animal test models in preclinical experimentation. Critical information on morphology and the molecular microenvironment of tumors is currently obtained and monitored using noninvasive, in vivo imaging methods. Detection of individual, small tumors […]
A PRECLINICAL SMALL ANIMAL IMAGING PLATFORM COMBINING MULTI-ANGLE PHOTOACOUSTIC AND FLUORESCENCE PROJECTIONS INTO CO-REGISTERED 3D MAPS
Authors: Weylan Thompson, Anthony Yu, Diego S. Dumani, Jason Cook, Mark A. Anastasio, Stanislav Y. Emelianov, Sergey A. Ermilov ABSTRACT We present the results on development of the 3D imaging platform combining photoacoustic tomography and fluorescence (PAFT) for preclinical and biological research. This combined multimodal imaging instrument addresses known deficiencies in sensitivity, spatial resolution, and […]
PRECLINICAL SMALL ANIMAL IMAGING PLATFORM PROVIDING CO-REGISTERED 3D MAPS OF PHOTOACOUSTIC RESPONSE AND FLUORESCENCE
Authors: Diego S. Dumani1,2, Anthony Yu1,2, Weylan Thompson3, Hans-Peter Brecht3, Vassili Ivanov3, Mark A. Anastasio4, Jason Cook5, Sergey A. Ermilov3, Stanislav Y. Emelianov1,2 ABSTRACT We report on the development of a preclinical 3D imaging platform integrating photoacoustic tomography and fluorescence (PAFT). The proposed multimodal imaging concept addresses known deficiencies in sensitivity, anatomical registration, and spatial […]