Tag: 3D

GPU-Accelerated 3D Volumetric X-Ray-Induced Acoustic Computed Tomography

Author(s): Donghyun Lee, Eun-Yeong Park, Seongwook Choi, Hyeongsub Kim, Jung-joon Min, Changho Lee, and Chulhong Kim ABSTRACT X-ray acoustic imaging is a hybrid biomedical imaging technique that can acoustically monitor X-ray absorption distribution in biological tissues through the X-ray induced acoustic effect. In this study, we developed a 3D volumetric X-ray-induced acoustic computed tomography (XACT) […]

Model-Based 3-D X-Ray Induced Acoustic Computerized Tomography

Authors: Prabodh Kumar Pandey; Siqi Wang; Leshan Sun; Lei Xing; Liangzhong Xiang ABSTRACT X-ray-induced acoustic (XA) computerized tomography (XACT) is an evolving imaging technique that aims to reconstruct the X-ray energy deposition from XA measurements. Main challenges in XACT are the poor signal-to-noise ratio and limited field-of-view, which cause artifacts in the images. We demonstrate the efficacy of model-based […]

A COMBINED ULTRASOUND AND PHOTOACOUSTIC IMAGING PLATFORM FOR CLINICAL RESEARCH APPLICATIONS

Author(s): Weylan Thompson, Hans-Peter Brecht, Sergey A. Ermilov, Vassili Ivanov ABSTRACT We present the continued development of a clinical ultrasound (US) imaging device with a photoacoustic (PA) mode. The combined USPA imaging platform is designed around a compact US component capable of B-mode, M-mode, color Doppler, and pulsed wave Doppler US imaging modes with a 128-element US probe. […]

CO-REGISTERED PHOTOACOUSTIC AND FLUORESCENT IMAGING OF A SWITCHABLE NANOPROBE BASED ON J-AGGREGATES OF INDOCYANINE GREEN

Authors: Diego S. Dumani, Hans-Peter Brecht, Vassili Ivanov, Ryan Deschner, Justin T. Harris, Kimberly A. Homan, Jason R. Cook, Stanislav Y. Emelianov, Sergey A. Ermilov ABSTRACT We introduce a preclinical imaging platform – a 3D photoacoustic/fluorescence tomography (PAFT) instrument augmented with an environmentally responsive dual-contrast biocompatible nanoprobe. The PAFT instrument was designed for simultaneous acquisition […]