Author(s): Weylan R. Thompson, Hans-Peter F. Brecht, Vassili Ivanov, Anthony M. Yu, Diego S. Dumani, Dylan J. Lawrence, Stanislav Y. Emelianov, Sergey A. Ermilov ABSTRACT SIGNIFICANCE To effectively study preclinical animal models, medical imaging technology must be developed with a high enough resolution and sensitivity to perform anatomical, functional, and molecular assessments. Photoacoustic (PA) tomography […]
Author: PhotoSound
BIODEGRADABLE AND BIOCOMPATIBLE SEMICONDUCTOR NANOCRYSTALS AS NIR-II PHOTOACOUSTIC IMAGING CONTRAST AGENTS
Author(s): Vinoin Devpaul Vincely, Swathi P. Katakam, Kristie Huda, Xingjian Zhong, Joshua C. Kays, Allison M. Dennis, Carolyn L. Bayer ABSTRACT Transabdominal imaging using photoacoustics (PA) is limited by optical attenuation of tissue due to high scattering and absorption in the near infrared (NIR) window. Tissue attenuation is lowered when imaging with longer wavelengths in the NIR window (> 950 nm). […]
IMPROVING PHOTOACOUSTIC IMAGING IN LOW SIGNAL-TO-NOISE RATIO BY USING SPATIAL AND POLARITY COHERENCE
Author(s): Qiuqin Mao, Weiwei Zhao, Xiaoqin Qian, Chao Tao, Xiaojun Liu ABSTRACT To suppress the noise and sidelobe of photoacoustic images, a method is proposed combined with spatial coherence and polarity coherence. In this method, PA signals are delayed, multiplied, then performed polarity coherence, and finally summed. The polarity of delayed-and-multiplied signals rather than the amplitude is considered in polarity coherence operation. The polarity coherence […]
DEEP LEARNING ENABLED REAL-TIME PHOTOACOUSTIC TOMOGRAPHY SYSTEM VIA SINGLE DATA ACQUISITION CHANNEL
Author(s): Hengrong Lan, Daohuai Jiang, Feng Gao, Fei Gao ABSTRACT Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements ultrasound array only using a single data acquisition (DAQ) channel. To reduce the channel number of DAQ, we superimpose 30 nearby […]
Y-NET: HYBRID DEEP LEARNING IMAGE RECONSTRUCTION FOR PHOTOACOUSTIC TOMOGRAPHY IN VIVO
Author(s): Hengrong Lan, Daohuai Jiang, Changchun Yang, Feng Gao, Fei Gao ABSTRACT Conventional reconstruction algorithms (e.g., delay-and-sum) used in photoacoustic imaging (PAI) provide a fast solution while many artifacts remain, especially for limited-view with ill-posed problem. In this paper, we propose a new convolutional neural network (CNN) framework Y-Net: a CNN architecture to reconstruct the initial PA pressure distribution by optimizing both raw data and beamformed images […]
RADIATION-INDUCED ACOUSTIC SIGNAL DENOISING USING A SUPERVISED DEEP LEARNING FRAMEWORK FOR IMAGING AND THERAPY MONITORING
Author(s): Zhuoran Jiang, Siqi Wang, Yifei Xu, Leshan Sun, Gilberto Gonzalez, Yong Chen, Q. Jackie Wu, Liangzhong Xiang, Lei Ren ABSTRACT Radiation-induced acoustic (RA) imaging is a promising technique for visualizing radiation energy deposition in tissues, enabling new imaging modalities and real-time therapy monitoring. However, it requires measuring hundreds or even thousands of averages to achieve satisfactory signal-to-noise ratios (SNRs). This repetitive […]
AUTOMATIC FORCE-CONTROLLED 3D PHOTOACOUSTIC SYSTEM FOR HUMAN PERIPHERAL VASCULAR IMAGING
Author(s): David C. Garrett, Jinhua Xu, Geng Ku, and Lihong V. Wang ABSTRACT We developed a system for whole-body human ultrasound tomography in reflection and transmission modes. A custom 512-element ultrasound receiver array with a rotating single-element ultrasound transmitter are used to generate 2D isotropically resolved images across the entire human cross-section. We demonstrate this […]
DUAL-SCAN PHOTOACOUSTIC TOMOGRAPHY FOR THE IMAGING OF VASCULAR STRUCTURE ON FOOT
Author(s): Chuqin Huang, Yanda Cheng, Wenhan Zheng, Robert W Bing, Huijuan Zhang, Isabel Komornicki, Linda M Harris, Praveen R Arany, Saptarshi Chakraborty, Qifa Zhou, Wenyao Xu, Jun Xia ABSTRACT Chronic leg ulcers are affecting approximately 6.5 million Americans, and they are associated with significant mortality, reduced quality of life, and high treatment costs. Since many […]
EVALUATION OF ULTRASOUND SENSORS FOR TRANSCRANIAL PHOTOACOUSTIC SENSING AND IMAGING
Author(s): Thomas Kirchner, Claus Villringer, and Jan Laufer ABSTRACT Significance: Biomedical photoacoustic (PA) imaging is typically used to exploit absorption-based contrast in soft tissue at depths of several centimeters. When it is applied to measuring PA waves generated in the brain, the acoustic properties of the skull bone cause not only strong attenuation but also […]
HIGH-SPEED THREE-DIMENSIONAL PHOTOACOUSTIC COMPUTED TOMOGRAPHY FOR PRECLINICAL RESEARCH AND CLINICAL TRANSLATION
Authors: Li Lin, Peng Hu, Xin Tong, Rui Cao, Xiaoyun Yuan, David C. Garrett, Junhui Shi, Konstantin Maslov & Lihong V. Wang ABSTRACT Photoacoustic computed tomography (PACT) has generated increasing interest for uses in preclinical research and clinical translation. However, the imaging depth, speed, and quality of existing PACT systems have previously limited the potential […]